Applied Biosystems/Ambion Privacy Policy
Applied Biosystems Limited Warranty Information

Ambion Registered Trademarks: Ambion, BrightStar, FirstChoice, MAXIscript, MEGAscript, mMESSAGE mMACHINE, NorthernMax, PROTEINscript, RETROscript, RNAlater, RNAqueous, RNaseAlert, RNaseZap, Silencer, Strip-EZ, and ULTRAhyb.

Ambion Trademarks: ActivePro, Agarose-HR, Agarose-LE, Agarose-LM, AgPath-ID, Ambi-miR, Anti-miR, ArrayControl, ArrayScript, BioDetect, CellReady, Cells-to-cDNA, Cells-to-CT, Cells-to-Signal, Century, Competimer, Decade, DECAprime, DECAtemplate, DNAclear, DNA-free, DNaseAlert, DNAZap, ElectroZap, flashPAGE, GeneAssist, GLOBINclear, GlycoBlue, HybSpeed, the "Just Say No to RNase" logo, KDalert, KinaseMax, LandMark, LeukoLOCK, MagMAX, MEGAclear, MEGAshortscript, MELT, MessageAmp, MessageSensor, MICROBEnrich, MICROBExpress, MicroPoly(A)Purist, Millennium, mirVana, mRNAlocator, NeoFX, NucAway, PARIS, pMIR-REPORT, Poly(A)Purist, Pre-miR, pSilencer, QuantumRNA, RecoverAll, Retic Lysate IVT, RiboPure, RNA Polymerase-Plus, RNase Cocktail, RNAsecure, "RNase-Free with Ambion", RNAwiz, RPA II, RPA III, siPORT, siPORTer, SlideHyb, StripAble, SUPERase•In, The RNAi Company, The siRNA Company, ToTALLY RNA, TotalPrep, TRIPLEscript, TURBO, and Xeno.

Other Trademarks:
AmpliTaq and AmpliTaq Gold are registered trademarks of Roche Molecular Systems, Inc.
Cy is a trademark of GE Healthcare.
FAM is a trademark of Applied Biosystems Inc. or its subsidiaries in the US and/or certain other countries.
Illumina is a registered trademark of Illumina, Inc.
LNA is a registered trademark of Exiqon A/S, Vedbaek, Denmark.
SOLiD is a trademark of Applied Biosystems Inc. or its subsidiaries in the US and/or certain other countries.
SuperTaq is a trademark of Enzyme Technologies Ltd.
SYBR is a registered trademark of Molecular Probes, Inc.
TaqMan is a registered trademark of Roche Molecular Systems, Inc.
TRI Reagent is a registered trademark of Molecular Research Center, Inc.

All other trademarks are the property of their respective owners.

Ambion Patents and Patents Pending: Anti-miR™ miRNA Inhibitor, ArrayScript™, Cells-to-cDNA™ II, Cells-to-Signal™, DNA-free™, GLOBINclear™, HybSpeed™ RPA, LCM Staining, LeukoLOCK™, MagMAX™, MEGAscript®, MEGAscript® RNAi, MEGAshortscript™, MELT™, MessageAmp™ II-Bacteria, MicroPoly(A)Purist™, mirVana™ miRNA Detection, mirVana™ miRNA Isolation, mirVana™ miRNA Labeling, mMESSAGE mMACHINE®, mMESSAGE mMACHINE® T7 Ultra, Poly(A)Purist™, Poly(A)Purist™ MAG-96 Automated, Pre-miR™ miRNA Precursor, QuantumRNA™ 18S and ß-Actin Internal Standards, Recombinant DNase, RecoverAll™, RNAlater®, RNAlater®-ICE, RNAsecure™, RNase III for siRNA generation, RPA II™, RPA III™, RT-PCR Competitor Construction, Silencer® siRNA Cocktail (RNase III), Silencer® siRNA Construction, Silencer® siRNA Labeling, siPORTer™-96, Strip-EZ®, SUPERase•In™, TRIPLEscript™, TURBO DNase™, and TURBO DNA-free™ technologies.

ALL PRODUCTS: FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.

AgPath-ID™ One-Step RT-PCR Reagents, Cells-to-cDNA™ II Kit, Cells-to-Signal™ Kit , MessageSensor™ RT Kit , mirVana™ qRT-PCR miRNA Detection Kit and Primer Sets, RETROscript® Kit, Silencer® siRNA Starter Kit: This product is compatible with the 5' nuclease detection and dsDNA-binding dye processes covered by patents owned or licensable by Applied Biosystems. No license under these patents is conveyed expressly, by implication, or by estoppel to the purchaser by the purchase of this product. Further information on purchasing licenses may be obtained by contacting the Director of Licensing, Applied Biosystems, 850 Lincoln Centre Drive, Foster City, California 94404, USA.

Amino Allyl MessageAmp™ II RNA Amplification Kits with CyDyes, Silencer® siRNA Labeling Kit-Cy3: The cyanine dyes in this product are manufactured on behalf of GE Healthcare under an exclusive license from Carnegie Mellon University and are covered by U.S. Patent Number 5,268,486 and 4,981,977 and other patents pending.
Cy and CyDye are trademarks of GE Healthcare.
FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE UNDER U.S. PATENT Nos. 5,268,486, 4,981,977.

Anti Reverse Cap Analog, mMessage mMachine® T7 Ultra Kit: Manufactured and sold under license under US Patent No. 7,074,596.

BrightStar® BioDetect™ Nonisotopic Detection Kit: CDP-Star® is a registered trademark of Tropix and is manufactured under U.S. Patent No. 5330900.

Illumina® TotalPrep™ RNA Amplification Kits : The Illumina® TotalPrep™ RNA Amplification Kits are covered by by US patents 5,256,555, 6,586,218, 6,586,219.

MagMAX™ Kits, MessageAmp™ Premier RNA Amplification Kit, MessageAmp™ II-96 RNA Amplification Kit, Amino Allyl MessageAmp™ II-96 RNA Amplification Kit: This product or portions thereof are manufactured and sold under license from GE Healthcare under U.S. Patent Nos. 5,523,231 and 5,681,946 and other foreign patents.

End Users are specifically not authorized to and are forbidden from reselling, transferring or distributing any products either as a stand alone product or as a component of another product.

MEGAscript® RNAi Kit: This product is covered by several patent applications owned by STANFORD. The purchase of this product conveys the buyer the limited, non-exclusive, non-transferable right (without the right to resell, repackage, or further sublicense) under these patent rights to perform the siRNA production methods claimed in those patent applications for research purposes solely in conjunction with this product. No other license is granted to the buyer whether expressly, by implication, by estoppel or otherwise. In particular, the purchase of this product does not include nor carry any right or license to use, develop, otherwise exploit this product commercially, and no rights are conveyed to the buyer to use the product or components of the product for any other purposes, including without limitation, provision of services to a third party, generation of commercial databases, or clinical diagnostics or therapeutics.
In addition, any user that purchases more that $5,000 in any calendar quarter may be outside the above research license and will contact STANFORD for a license.
This product is sold pursuant to a license from STANFORD, and STANFORD reserves all other rights under these patent rights. For information on purchasing a license to the patent rights for uses other than in conjunction with this product or to use this product for purposes other than research, please contact STANFORD at, 650-723-0651. This is STANFORD reference S02-028.

NOTICE TO PURCHASER:
Purchase of this product gives the user rights under U.S. Patent No. 6,506,559, and its foreign equivalents, to use this product for life science research, not for use in humans or clinical diagnostics.

MessageAmp™ Premier RNA Amplification Kit : The MessageAmp™ Premier RNA Amplification Kit is covered by one or more of the following US Patents 5,514,545; 5,723,290; 5,958,688; 5,021,335; 5,168,038; 5,545,522;
5,716,785; 5,891,636; 6,291,170; 5,256,555; 6,586,218; and 6,586,219.

mirVana™ miRNA Probe Set: The purchase of Ambion products does not convey any license under any patent rights owned by Oxford Gene Technology IP Limited (“OGT”) including any right to make or use oligonucleotide arrays under OGT’s patents, i.e. US, European, Japanese patents and patent applications deriving from WO 89/10977, WO 90/03382 and WO 96/31622. Please contact OGT to enquire about a license under OGT’s patents at licensing@ogt.co.uk. Further details can be found at www.ogt.co.uk.

mirVana™ miRNA Reference Panel: NOTICE TO PURCHASER: LIMITED LICENSE This product is sold under licensing arrangement between Ambion, Inc. and Rosetta Genomics. The purchase price of this product includes limited, nontransferable rights under patents and/or pending patent applications owned by Rosetta Genomics to use the product solely within the field of research. Further information on purchasing licenses under the Rosetta patent applications may be obtained by contacting Rosetta Genomics, Director of Business Development, BD@Rosettagenomics.com (201-255-5900).

pMIR-REPORT™ miRNA Expression Reporter Vector: This product or the use of this product is covered by U.S. Patent Nos. 5,583,024, 5,674,713, and 5,700,673 owned by The Regents of the University of California.
This product is for in vitro research use only. It is not to be used for commercial purposes. Use of this product to produce products for sale or for diagnostic, therapeutic or drug discovery purposes is prohibited. In order to obtain a license to use this product for commercial purposes, contact The Regents of the University of California.

Pre-miR™ miRNA Starter Kit:
NOTICE TO PURCHASER: LIMITED LICENSE
A license to perform the patented 5' Nuclease Process for research is obtained by the purchase of (i) both Licensed Probe and Authorized 5' Nuclease Core Kit, (ii) a Licensed 5' Nuclease Kit, or (iii) license rights from Applied Biosystems.

The Pre-miR™ miRNA Precursor Starter Kit contains Licensed Probe. Use of this product is covered by one or more of the following US patents and corresponding patent claims outside the US: 5,538,848, 5,723,591, 5,876,930, 6,030,787, 6,258,569, and 5,804,375 (claims 1-12 only). The purchase of this product includes a limited, non-transferable immunity from suit under the foregoing patent claims for using only this amount of product for the purchaser's own internal research. Separate purchase of an Authorized 5' Nuclease Core Kit would convey rights under the applicable claims of US Patents Nos. 5,210,015 and 5,487,972, and corresponding patent claims outside the United States, which claim 5' nuclease methods. No right under any other patent claim and no right to perform commercial services of any kind, including without limitation reporting the results of purchaser's activities for a fee or other commercial consideration, is conveyed expressly, by implication, or by estoppel. This product is for research use only. Diagnostic uses under Roche patents require a separate license from Roche. Further information on purchasing licenses may be obtained from the Director of Licensing, Applied Biosystems, 850 Lincoln Centre Drive, Foster City, California 94404, USA.

pSilencer™ Vectors: Licensing Information

Silencer® siRNAs and Silencer® Select siRNAs (Custom, Pre-designed, Validated, Controls, Libraries), Silencer® siRNA Cocktail Kit (RNase III), Silencer® siRNA Construction Kit, Silencer® siRNA Labeling Kits, Silencer® siRNA Starter Kit, Silencer® siRNA Transfection II Kit, Silencer® CellReady siRNA Transfection Optimization Kit, siPORT™ siRNA Electroporation Kit:
This product is licensed under European Patents 1144623, 1214945 and foreign equivalents from Alnylam Pharmaceuticals, Inc., Cambridge, USA and is provided only for use in academic and commercial research including in vitro and in vivo identification and validation of drug targets (but excluding the evaluation or characterization of this product as the potential basis for a siRNA-based drug) and not for any other commercial purposes. Information about licenses for commercial use (including discovery and development of siRNA-based drugs) is available from Alnylam Pharmaceuticals, Inc., 300 Third Street, Cambridge, MA 02142, USA.

Ambion siRNA products are manufactured under license from the Massachusetts Institute of Technology to U.S. Patent Nos. 7,056,704 and 7,078,196 and pending counterparts. The purchaser of the product may use it for research use only.

NOTICE TO PURCHASER:
Purchase of this product gives the user rights under U.S. Patent No. 6,506,559, and its foreign equivalents, to use this product for life science research, not for use in humans or clinical diagnostics.

Silencer® Select siRNAs (Custom, Pre-designed, Validated, Controls, Libraries):
Locked Nucleic Acids are covered by patents and patent applications owned by Exiqon A/S. This product is for research use only and not for diagnostic or therapeutic use. The products may be used only for the buyer's internal research purposes and not for commercial use except for providing a service to research customers. The buyer may not resell products in their original or any modified form.

Silencer® Cy3 labeled siRNAs, siPORT™ siRNA Electroporation Kit, Cy™3 dye-labeled Anti-miR™ Negative Control, Cy™3 dye-labeled Pre-miR™ Negative Control : This product or portions thereof is manufactured under license from Carnegie Mellon University under DE3943862 and GE Healthcare under U.S. Patent Numbers 5,808,044 and 5,556,959 and related Patents.

Silencer® siRNA Labeling Kits: The Cy3 and Fluorescein Labeling Reagents are manufactured for Ambion by Mirus Bio Corporation.

siPORT™ Amine Transfection Agent, siPORT™ XP-1 Transfection Agent: Manufactured for Ambion by Mirus Bio Corporation.

SuperTaq™ DNA Polymerase: Use of this product is covered by one or more of the following US patents and corresponding patent claims outside the US : 5,079,352, 5,789,224, 5,618,711, 6,127,155 and claims outside the US corresponding to US Patent No. 4,889,818. The purchase of this product includes a limited, non-transferable immunity from suit under the foregoing patent claims for using only this amount of product for the purchaser's own internal research. No right under any other patent claim (such as the patented 5' Nuclease Process claims in US Patents Nos. 5,210,015 and 5,487,972), no right to perform any patented method, and no right to perform commercial services of any kind, including without limitation reporting the results of purchaser's activities for a fee or other commercial consideration, is conveyed expressly, by implication, or by estoppel. This product is for research use only. Diagnostic uses under Roche patents require a separate license from Roche. Further information on purchasing licenses may be obtained by contacting the Director of Licensing, Applied Biosystems, 850 Lincoln Centre Drive, Foster City, California 94404 , USA.

SuperTaq™ Plus DNA Polymerase: Use of this product is covered by one or more of the following US patents and corresponding patent claims outside the US: 5,079,352, 5,789,224, 5,618,711, 6,127,155, 5,677,152 (claims 1-23 only) and 5,773,258 (claims 1 and 6 only), and claims outside the US corresponding to US Patent No. 4,889,818. The purchase of this product includes a limited, non-transferable immunity from suit under the foregoing patent claims for using only this amount of product for the purchaser's own internal research. No right under any other patent claim (such as the patented 5' Nuclease Process claims in US Patents Nos. 5,210,015 and 5,487,972) and no right to perform commercial services of any kind, including without limitation reporting the results of purchaser's activities for a fee or other commercial consideration, is conveyed expressly, by implication, or by estoppel. This product is for research use only. Diagnostic uses require a separate license from Roche. Further information on purchasing licenses may be obtained by contacting the Director of Licensing, Applied Biosystems, 850 Lincoln Centre Drive, Foster City, California 94404, USA.

SYBR® Green Cells-to-CT™ Kits: Notice To Purchaser: Limited License Use of this product is covered by one or more of the following US patents and corresponding patent claims outside the US: 5,079,352, 5,789,224, 5,618,711, 6,127,155, 5994,056, and 6,171,785. The purchase of this product includes a limited, non-transferable immunity from suit under the foregoing patent claims for using only this amount of product for the purchaser’s own internal research. No right under any other patent claim (such as apparatus or system claims in US Patent No. 6,814,934) and no right to perform commercial services of any kind, including without limitation reporting the results of purchaser’s activities for a fee or other commercial consideration, is conveyed expressly, by implication, or by estoppel. This product is for research use only. Human diagnostic uses under Roche patents require a separate license from Roche. Further information on purchasing licenses may be obtained from the Director of Licensing, Applied Biosystems, 850 Lincoln Centre Drive, Foster City, California 94404, USA.

Notice To Purchaser: Limited License This product is sold under licensing arrangements between Applied Biosystems and Invitrogen Corporation. The purchase price of this product includes limited, nontransferable rights under U.S. Patent 5,035,996 and foreign equivalents owned by Invitrogen Corporation to use only this amount of the product to practice the claims in said patents solely for activities of the purchaser within the field of research. Further information on purchasing licenses under the above patents may be obtained by contacting the Director, Corporate Development at Invitrogen Corporation, 1600 Faraday Avenue, PO Box 6482, Carlsbad, California 92008.

The SYBR® Green dye is sold pursuant to a limited license from Molecular Probes, Inc. under U.S. Patent No. 5,436,134 and 5,658,751 and corresponding foreign patents and patent applications.

TaqMan® Cells-to-CT™ Control Kit: Practice of the patented 5’ Nuclease Process requires a license from Applied Biosystems. The purchase of this product includes an immunity from suit under patents specified in the product insert to use only the amount purchased for the purchaser's own internal research when used with the separate purchase of an Authorized 5’ Nuclease Core Kit. No other patent rights are conveyed expressly, by implication, or by estoppel. For further information on purchasing licenses contact the Director of Licensing, Applied Biosystems, 850 Lincoln Centre Drive, Foster City, California 94404, USA.

TaqMan® Fast Cells-to-CT™ Kit, TaqMan® Gene Expression Cells-to-CT™ Kit: Practice of the patented 5’ Nuclease Process requires a license from Applied Biosystems. The purchase of the TaqMan® Gene Expression Cells-to-CT™ Kit includes an immunity from suit under patents specified in the product insert to use only the amount purchased for the purchaser's own internal research when used with the separate purchase of a Licensed Probe. No other patent rights are conveyed expressly, by implication, or by estoppel. For further information on purchasing licenses contact the Director of Licensing, Applied Biosystems, 850 Lincoln Centre Drive, Foster City, California 94404, USA.

Purchase of this product is accompanied by a limited license under U.S. Patent 5,035,996 and foreign equivalents to use for research.

TRI Reagent® is a registered trademark of Molecular Research Center, Inc. TRI Reagent® is a subject of US Patent 5,346,994.

Applied Biosystems/Ambion Privacy Policy

Applied Biosystems Limited Warranty Information

Some of the products listed on this web site are known to be toxic or cancer-suspect agents and are so labeled. Such products must be handled with extreme caution. Many other products have not been tested for toxicity. The absence of a specific warning should not be interpreted to mean that the products have been proven to be nontoxic. Material Safety Data Sheets are provided for all products.